Use of optical tweezers to probe epithelial mechanosensation

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Use of optical tweezers to probe epithelial mechanosensation.

Cellular mechanosensation mechanisms have been implicated in a variety of disease states. Specifically in renal tubules, the primary cilium and associated mechanosensitive ion channels are hypothesized to play a role in water and salt homeostasis, with relevant disease states including polycystic kidney disease and hypertension. Previous experiments investigating ciliary-mediated cellular mecha...

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ژورنال

عنوان ژورنال: Journal of Biomedical Optics

سال: 2010

ISSN: 1083-3668

DOI: 10.1117/1.3316378